Viscum Fraxini 2

Immunomodulator / Cytotoxic

Properties and actions:

Viscum Fraxini 2, mistletoe extract, stimulates the T and B-Cell components of the immune system, which leads to the expression and release of cytokines, proliferation and activation of immuno-competent cells; especially natural killer cells, T-Cytotoxic cells and lymphokine activated killer cells.
Treatment with 
Viscum Fraxini 2 is associated with an improvement of the quality of life of cancer patients.
Viscum Fraxini 2 stimulates the secretion of endogenous β-Endorphins which leads to the control of pain.
Viscum Fraxini 2 contains lectins which enhance apoptosis and viscotoxins which exert direct cytotoxic effect on tumor cells. 

Indications:

  • Pleurodesis in malignant pleural effusion.
  • Supportive for inoperable hepatocellular carcinoma patients.
  • Complementary in breast cancer. 

Dosage:

  • Dose in malignant pleural effusion:
5 ampoules of Viscum Fraxini 2 mixed with 10 ml of glucose 5% intrapleural weekly till complete pleurodesis or up to six weeks. 
  • Dose in inoperable hepatocellular carcinoma:
Two ampoules subcutaneous per week are given till maximum response and / or 3 ampoules intralesional (sonar guided) weekly for 6 weeks, course can be repeated after 8 weeks, till maximum response. 
  • Dose in breast cancer:
One ampoule subcutaneous weekly during the course of chemotherapy.
For full mode of administration refer to Viscum product monograph. 

Contraindications:

  • In acute inflammatory conditions or if the temperature is above 38°C: treat- ment should be discontinued until the fever and the inflammation subside.
  • Known hypersensitivity to Mistletoe preparations.
  • Studies on use for infants and young children are not available.
  • Pregnancy use should be limited to spe- cial circumstances. 

Side Effects:

  • For full information about side effects refer to Viscum Fraxini 2 product monograph. 

Each ampoule of 1 ml contains:

Mistletoe extracte: 15mg (Equivalent to 10000 ng Lectins)

Pack size:

3 ampoules 1 ml of aqueous solution for injection

Precautions / Drug interactions:

Keep in dry and cool place (8-16°C) in the lower part of the refrigerator. Keep out of reach of children.