Safamood

Psychosomatic Disorders

Properties and actions:

Safamood regulates motility, sensitivity, and secretion of fluids of GIT.
safamood inhibits synaptic reuptake of serotonin and to a lesser extent norepinephrine, resulting in increased levels of these neurotransmitters in the synapse and modulates the level of cytokines so it has an antidepressant effect and reduces the psychosomatic symptoms.
Safamood has a potential analgesic effect through activation of endogenous paininhibitory system in the brain.
Safamood exerts a mild anxiolytic action through the inhibition of Gamma Amino Butyric Acid (GABA) reuptake pump. 
Safamood is well tolerated and causes no psychological or physical dependence, muscle relaxation, or cognitive impairment. 

Indications:

  • Psychosomatic symptoms e.g. psychogenic GIT disturbances, irritable bowel syndrome 

Dosage:

  • Less otherwise prescribed by the physician; one tablet 2-3 times/daily  

Contraindications:

  • Pregnancy and lactation

Side Effects:

  • None reported within the therapeutic dose 

Each tablet contains:

  • Hypericum perforatum dry extract 250 mg (Standardized to contain minimum 0.12% dianthrones calculated as Hypericine)
  • Vitamin C 50 mg 

Pack size:

20 tablets in 2 blisters

Precautions / Drug interactions:

  • Plasma level of Warfarin, Digoxin, Theophylline, and Contraceptive pills may be reduced with Safamood as it has enzyme inducing effects accelerating their metabolism
  • Concomitant use with Selective Serotonin Reuptake Inhibitors (SSRIs) may cause serotonin syndrome